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Article in Japanese
Abstract
Case Report
A case of eosinophilic granulomatosis with polyangiitis and various symptoms, treated effectively with mepolizumab
Daisuke Jingu Satoshi Ubukata Kosuke Sato Takehiro Yajima Hiroshi Watanabe Hiroshi Takahashi
Department of Respiratory Medicine, Saka General Hospital
ABSTRACT
A 46-year-old male patient, who was undergoing treatment for erythema and blisters on his legs, developed respiratory failure and lung shadows. He was treated with steroids, and further examination revealed eosinophilic granulomatosis with polyangiitis (EGPA). While tapering steroids, he experienced asymmetric edema, muscle swelling with pain, and neurological disorder, as well as another rise in peripheral eosinophil count. His symptoms improved with a re-increase of steroids. Mepolizumab was administered to allow a reduction in steroid dosage, which was achieved without recurrence of symptoms. It is important to recognize the diverse clinical symptoms of EGPA and to diagnose and treat them accordingly.
KEYWORDS
Eosinophilic granulomatosis with polyangiitis (EGPA) Mepolizumab Eosinophil Antineutrophil cytoplasmic antibody (ANCA) relapse
Received 18 Jun 2024 ／ Accepted 26 Sep 2024
AJRS, 14(1): 34-38, 2025
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