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Article in Japanese
Abstract
Original Article
The usefulness of the COPD assessment test (CAT) in the management of nontuberculous mycobacterial pulmonary disease
Hideto Oshita Misato Ogata Asami Inoue Yuka Sano Koji Yoshioka Yasuhiko Ikegami, Naoki Yamaoka
Department of Respiratory Medicine, Federation of National Public Service and Affiliated Personnel Mutual Aid Associations, Yoshijima Hospital
ABSTRACT
In our study of 109 patients with nontuberculous mycobacterial pulmonary disease (NTM-PD), patients with high chronic obstructive pulmonary disease (COPD) assessment test (CAT) scores ≥10 points) at first visit had higher inflammatory markers and higher rates of smear positivity than patients with low CAT scores. CAT improvement (decrease of ≥2 points) was seen in 18 of 29 patients 6 months after initiating multidrug therapy. Although the rate of culture conversion was significantly lower in patients with high pretreatment CAT scores than in patients with low scores, the CAT improvement rate after treatment was high, and there were many cases in which CAT improved without culture conversion. Assessing health-related quality of life (HRQOL) using CAT could serve as a valuable indicator of treatment efficacy for NTM-PD.
KEYWORDS
Nontuberculous mycobacterial pulmonary disease (NTM-PD) Health-related quality of life
Received 19 Sep 2024 ／ Accepted 31 Oct 2024
AJRS, 14(1): 9-14, 2025
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