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Article in Japanese
Abstract
Case Report
A case of disseminated tuberculosis due to M. bovis after BCG intravesical infusion therapy
Ibuki Kosai Masahiro Shimada Kengo Sato Yuka Sasaki Atsuhisa Tamura Hirotoshi Matsui
Center for Pulmonary Diseases, National Hospital Organization Tokyo National Hospital
ABSTRACT
An 84-year-old man, with a history of pulmonary tuberculosis and a previous intravesical Bacillus Calmette-Guérin (BCG) injection for bladder cancer, presented with a subcutaneous abscess located in the anterior thorax. A smear of the abscess content tested positive for acid-fast bacilli. Subsequent chest computed tomography imaging revealed multiple bilateral granular nodules, leading to initiation of the standard treatment with four anti-tuberculosis drugs. However, Interferon-γ release assay was negative, necessitating further investigation. Multiplex PCR analysis was conducted, which confirmed Mycobacterium bovis BCG as the causative agent of the patient's condition.
KEYWORDS
Bacillus Calmette-Guérin (BCG) intravesical infusion therapy Disseminated tuberculosis Multiplex polymerase chain reaction
Received 20 Jul 2024 ／ Accepted 22 Jul 2024
AJRS, 13(6): 292-295, 2024
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