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Abstract

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Article in Japanese

Case Report

A case of anti-TIF1-γ antibody-positive dermatomyositis with small cell lung cancer after COVID-19 vaccination

Hiroki Tomita  Akira Takeuchi  Minami Sakakura 

Department of Respiratory Medicine, Nagoya Central Hospital

ABSTRACT

A 77-year-old woman presented with rash, muscle pain, muscle weakness, and dysphagia after the third dose of COVID-19 vaccine. Chest computed tomography showed a mass shadow in the right lower lobe. Finally, she was diagnosed with extensive-stage small-cell lung cancer and anti-transcriptional intermediary factor (TIF)1-γ antibody-positive dermatomyositis. Chemotherapy and systemic corticosteroids improved the symptoms of dermatomyositis and produced a partial response to lung cancer. We should consider dermatomyositis when rash or muscle symptoms appear after COVID-19 vaccination.

KEYWORDS

Coronavirus disease 2019  Vaccine  Dermatomyositis  Anti- transcriptional intermediary factor (TIF) 1-γ antibody  Small cell lung cancer 

Received 3-Apr-24 / Accepted 5-Jun-24

AJRS, 13(5): 255-259, 2024

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