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Article in Japanese
Abstract
Case Report
A case of idiopathic pulmonary fibrosis with recurrent pneumothorax during nintedanib therapy
Haruka Nakatani Shinsuke Shiotsu Shunya Tanaka Taisuke Tsuji Tatsuya Yuba Chieko Takumi
Department of Respiratory Medicine, Japanese Red Cross Society Kyoto Daiichi Hospital
ABSTRACT
An 80-year-old man with idiopathic pulmonary fibrosis underwent a chest computed tomography (CT) scan, which revealed progressive fibrosis and honeycombing at the lung bases. He started nintedanib and developed a pneumothorax 8 months later. The patient stopped taking nintedanib and rested, which quickly resolved his condition. He resumed nintedanib treatment and was admitted to the hospital 5 months later for another pneumothorax. We inserted chest tubes because he experienced a further pneumothorax and performed pleurodesis. However, these measures were ineffective. Therefore, a surgical repair was performed. Unfortunately, the patient developed postoperative pneumonia and died. Nintedanib initiation should be carefully considered in patients who are at high risk of developing a pneumothorax.
KEYWORDS
Nintedanib Idiopathic pulmonary fibrosis Pneumothorax Pulmonary function Emphysematous change
Received 4-Mar-24 ／ Accepted 11-Jun-24
AJRS, 13(5): 228-231, 2024
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