Annals of The Japanese Respiratory Society:A case of chylothorax associated with Stage IV primary lung cancer treated by lymphangiography

Vol.13 No.5 Table of Contents

Abstract

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Article in Japanese

Case Report

A case of chylothorax associated with Stage IV primary lung cancer treated by lymphangiography

Saki Nakajima^a Mio Ashida^a Satoshi Watanabe^a Takuhide Utsunomiya^a Yukimasa Sakai^b Keita Kudo^a

^aDepartment of Medical Oncology, National Hospital Organization, Osaka Minami Medical Center
^bDepartment of Radiology, National Hospital Organization, Osaka Minami Medical Center

ABSTRACT

A 71-year-old woman was diagnosed with Stage IVA primary lung adenocarcinoma. Despite treatment with gefitinib, the cancer spread to the right hilar lymph nodes, and chylous intrapulmonary and right pleural effusion appeared. Therefore, osimertinib was initiated as a second-line treatment. Although the tumor size reduced, the pleural effusion continued to increase. Because no improvement was observed with dietary treatment, lymphangiography was performed. Although it was difficult to identify the site of leakage, the pleural effusion decreased. Lymphangiography is potentially a therapeutic tool for the treatment of non-traumatic chylothorax.

KEYWORDS

Epidermal growth factor receptor (EGFR) mutation-positive Primary lung cancer Chylothorax Lymphangiography

Received 25-Dec-23 ／ Accepted 17-May-24

AJRS, 13(5): 218-222, 2024

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