Annals of The Japanese Respiratory Society:A case of <i>KRAS</i> mutation-positive invasive mucus-producing lung adenocarcinoma with high serum CA19-9 levels

Vol.13 No.5 Table of Contents

Abstract

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Article in Japanese

Case Report

A case of KRAS mutation-positive invasive mucus-producing lung adenocarcinoma with high serum CA19-9 levels

Yuki Seike^a Kazuyoshi Watanabe^a Task Iwabuchi^a Tamami Sakai^a Seiji Yano^b

^aDepartment of Respiratory Medicine, Japan Community Health Care Organization Kanazawa Hospital
^bDepartment of Respiratory Medicine, Kanazawa University Hospital

ABSTRACT

The patient, a 77-year-old man, was diagnosed with invasive mucus-producing lung adenocarcinoma (cT4N3M1b stage IVA, KRAS G12C positive) and started chemotherapy with carboplatin, pemetrexed, and pembrolizumab. The tumors markedly reduced in size. Pembrolizumab-containing chemotherapy was effective in KRAS mutation-positive invasive mucus-producing lung adenocarcinoma.

KEYWORDS

Invasive mucinous adenocarcinoma KRAS G12C Pembrolizumab

Received 16-Apr-24 ／ Accepted 28-Jun-24

AJRS, 13(5): 213-217, 2024

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