A case of allergic bronchopulmonary aspergillosis with development of eosinophilic pneumonia in areas separate from those containing mucus plugs
Yuto Akiyamaa Takashi Ishiguroa Naomi Takatab Yotaro Takakua Yoshihiko Shimizuc
aDepartment of Respiratory Medicine, Saitama Cardiovascular and Respiratory Center
bDepartment of Radiology, Saitama Cardiovascular and Respiratory Center
cDepartment of Pathology, Saitama Cardiovascular and Respiratory Center
A 65-year-old woman with asthma was admitted to our hospital with fever, eosinophilia, and abnormal shadows on chest radiography and computed tomography (CT). Chest CT showed infiltrates and ground-glass opacities in both lung fields, especially both upper lobes, and localized central bronchiectasis with highly attenuated mucoid impaction in B9b of the right basal bronchus. We extracted a mucus plug, which showed accumulation of eosinophils, by bronchoscopy. Elevation of serum total IgE and positivity for IgE and precipitating antibodies against Aspergillus fumigatus were confirmed. We diagnosed the patient as having allergic bronchopulmonary aspergillosis (ABPA). Although central bronchiectasis was localized in only one bronchial subsegment of the right lower lobe, eosinophilic pneumonia was widely distributed in both lung fields of this patient. The case is valuable when considering the mechanism of eosinophilic pneumonia accompanying A
Allergic bronchopulmonary aspergillosis (ABPA) Central bronchiectasis (CB) Eosinophilic pneumonia (EP) Mucoid impaction of the bronchi (MIB) Mucus plug
Received 10 Jan 2024 / Accepted 18 Mar 2024
AJRS, 13(4): 198-201, 2024