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Abstract
Case Report
A case of adrenocortical carcinoma that was difficult to differentiate from adrenal metastasis of lung adenocarcinoma
Megumi Kanekoa,b Yoichi Tagamia Yu Haraa Hironori Tamurab Hiroko Minamic Takeshi Kanekoa
aDepartment of Pulmonology, Yokohama City University Graduate School of Medicine
bDepartment of Pulmonology, Chigasaki Municipal Hospital
cDepartment of Pathology, Yokohama City University Hospital
ABSTRACT
A 44-year-old man was diagnosed with adenocarcinoma of the lung and a metastasis in the left adrenal gland. He was treated with cisplatin, pemetrexed, and bevacizumab. However, during maintenance therapy with pemetrexed and bevacizumab, the primary tumor and adrenal tumor continued to grow; therefore, his treatment was switched to second-line therapy (single-agent therapy with docetaxel). The lung adenocarcinoma stopped growing, but the adrenal tumor continued to grow, and was suspected of being a synchronous oligometastasis. The adrenal tumor was subsequently resected, and histopathological examination revealed it to be an adrenocortical carcinoma. This is an extremely rare case of adrenocortical carcinoma occurring simultaneously with primary lung cancer.
KEYWORDS
Lung adenocarcinoma Adrenocortical carcinoma Metastatic adrenal tumor Multiple primary cancers Oligometastatic disease
Received 22 Aug 2023 ／ Accepted 1 Apr 2024
AJRS, 13(4): 184-188, 2024
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