Full Text of PDF (424k)
Article in Japanese
Abstract
Case Report
A case of MPO-ANCA-positive granulomatosis with polyangiitis with pleuritis as the only complication
Nobuhiro Shimura* Hirotsugu Hasegawa Kotaro Yamada Ryo Shimota Hiroki Sugiyama Koshi Yokomura
Department of Respiratory Medicine, Respiratory Disease Center, Seirei Mikatahara General Hospital
*Present address: Department of Respiratory Medicine, Shizuoka City Shizuoka Hospital
ABSTRACT
An 82-year-old man presented with nosebleeds, exertional dyspnea, and dry cough, with a right pleural effusion noted on chest radiography. Because the pleural effusion was a lymphocyte-predominant exudative pleural effusion without malignant findings or high adenosine deaminase, all cultures were negative, and the blood serum MPO-ANCA test was positive, pleuritis caused by ANCA-associated vasculitis was suspected. He was diagnosed with granulomatosis with polyangiitis complicated by pleuritis because he met both the Japanese diagnostic criteria and the Watts classification criteria. He was treated with corticosteroids and achieved remission. Although pleuritis caused by ANCA-associated vasculitis is a difficult condition to recognize, we report it here because it is important for differentiation.
KEYWORDS
Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AVV) Granulomatosis with polyangiitis (GPA) Pleural effusion Pleuritis
Received 21 Dec 2023 ／ Accepted 12 Mar 2024
AJRS, 13(4): 160-164, 2024
Copyright © The Japanese Respiratory Society All Rights Reserved.