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Article in Japanese
Abstract
Case Report
A case of antineutrophilic cytoplasmic antibody-associated vasculitis presenting with marked visual loss due to hypertrophic pachymeningitis and optic perineuritis
Tatsuki Tsurugaa Hajime Fujimotoa Kumiko Katob Toshiyuki Itoa Kazuki Furuhashia Tetsu Kobayashia
aDepartment of Respiratory Medicine, Mie University School of Medicine Hospital
bDepartment of Ophthalmology, Mie University School of Medicine Hospital
ABSTRACT
The patient, an 80-year-old man, had been diagnosed with antineutrophilic cytoplasmic antibody (ANCA)-associated vasculitis and was treated with prednisolone. He was urgently admitted to our hospital due to a sudden loss of vision (photoplegia) in his left eye and headache. Contrast-enhanced magnetic resonance imaging of the head revealed hypertrophic pachymeningitis and optic perineuritis. He received steroid pulse therapy, which improved his vision significantly, and was discharged after starting cyclophosphamide pulse therapy. Hypertrophic pachymeningitis and optic perineuritis are rare complications that can occur during the course of ANCA-associated vasculitis. They require prompt diagnosis and treatment in collaboration with other specialties, as they may impair the patient's quality of life and survival.
KEYWORDS
Antineutrophilic cytoplasmic antibody (ANCA)-associated vasculitis (AAV) Eosinophilic granulomatosis with polyangiitis (EGPA) Hypertrophic pachymeningitis (HP) Optic perineuritis (OPN)
Received 7 Dec 2023 ／ Accepted 26 Feb 2024
AJRS, 13(3): 116-120, 2024
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