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Article in Japanese
Abstract
Case Report
A case of disseminated bacillus Calmette-Guérin infection associated with hemophagocytic syndrome
Yasuhiro Umekagea Akari Yagitab Hiraku Yanadab Ryota Shigakib Yoshinori Minamib Takaaki Sasakib
aDepartment of Infection Control, Asahikawa Medical University Hospital
bDepartment of Respiratory Medicine, Asahikawa Medical University Hospital
ABSTRACT
We present the case of an 81-year-old male who developed disseminated bacillus Calmette-Guérin (BCG) infection following intravesical BCG therapy for superficial bladder cancer. He presented with thrombocytopenia and radiological evidence of a lung shadow. The bone marrow biopsy confirmed the presence of hemophagocytosis. Disseminated BCG infection was diagnosed based on positive cultures both from sputum and blood samples for Mycobacterium bovis. The lung shadow improved with steroids and was attributed to a hypersensitivity reaction to BCG. Disseminated BCG disease can manifest with BCG-related pneumonia. In the case of disseminated BCG, the occurrence of hemocytopenia should prompt consideration of an associated hemophagocytic syndrome.
KEYWORDS
Disseminated bacillus Calmette-Guérin (BCG) Hemophagocytic syndrome
Received 22 Aug 2023 ／ Accepted 27 Nov 2023
AJRS, 13(2): 78-82, 2024
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