Annals of The Japanese Respiratory Society:An autopsy case of desquamative interstitial pneumonia comorbid with severe pulmonary hypertension

Vol.13 No.2 Table of Contents

Abstract

Full Text of PDF (539k)

Article in Japanese

Case Report

An autopsy case of desquamative interstitial pneumonia comorbid with severe pulmonary hypertension

Hiroki Takechi^a,b Hiroshi Kuraishi^a Yuki Todoroki^a Ryota Ozawa^a Manabu Yamamoto^a Ichiro Ito^c

^aDepartment of Pulmonary Medicine, Nagano Red Cross Hospital
^bDepartment of Pulmonary Medicine, Saku Central Hospital Advanced Care Center
^cDepartment of Pathology, Nagano Red Cross Hospital

ABSTRACT

After developing a chronic cough, a 46-year-old male was diagnosed with desquamative interstitial pneumonia (DIP) by thoracoscopic lung biopsy 16 years ago. Despite smoking cessation and systemic steroid therapy, symptoms of right heart failure began to appear three years ago. He was referred to our hospital because of his worsening respiratory condition. Right heart catheterization revealed severe pulmonary hypertension, and he died irrespective of treatment with pulmonary vasodilators and diuretics.
In some DIP patients, fibrosis progresses even after smoking cessation and steroid therapy, leading to severe respiratory failure and pulmonary hypertension. In patients with progressive fibrosis, it is especially important to evaluate pulmonary hypertension, and lung transplantation should be considered in severe cases.

KEYWORDS

Desquamative interstitial pneumonia (DIP) Pulmonary hypertension

Received 8 Sep 2023 ／ Accepted 1 Nov 2023

AJRS, 13(2): 59-63, 2024

Search for	AJRS(after 2012) JJRS(before 2011) Both of which
Year	equal after before
Volume	equal after before	Number	equal after before
Title		Author
Abstract		Keywords