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Abstract

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Article in Japanese

Case Report

A case of pneumoconiosis after exposure to titan dioxide powder

Taisaku Koyanagi  Takumi Kishimoto 

Department of Internal Medicine, Okayama Rosai Hospital

ABSTRACT

We report a case of pneumoconiosis after exposure to titan dioxide powder for more than 20 years. Chest X-ray showed ground-glass opacities in all the lung fields, and high-resolution computed tomography (HRCT) showed peripheral centrilobular blurred nodular shadows. Titan dioxide was confirmed on the specimen obtained via bronchoalveolar lavage and transbronchial biopsy. Titan dioxide was deposited mainly around the pulmonary artery and peribronchiolar area. Furthermore, mediastinal and abdominal lymph node swelling was observed at high attenuation. HRCT showed mild fibrosis in the left inferior region, which was verified via biopsy. To our knowledge, this is the first case of pneumoconiosis with titan deposition in the peribronchial area, mediastinal and abdominal lymph node swelling and mild fibrosis of the lungs after long-term inhalation of titan dioxide powder.

KEYWORDS

Titanium oxide  Packing  Pneumoconiosis  Alveolar macrophage  Centrilobular dust deposition 

Received 29 May 2023 / Accepted 23 Aug 2023

AJRS, 12(6): 329-333, 2023

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