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Article in Japanese
Abstract
Case Report
Severe pneumonia caused by Legionella pneumophila successfully treated with endotoxin adsorption and nitric oxide inhalation therapy
Tomoko Iriyamaa Masafumi Yamaguchia Tsukasa Nakanishib Yoko Tsunodaa Keiko Narumiyaa Yasutaka Nakanoa
aDivision of Respiratory Medicine, Department of Internal Medicine, Shiga University of Medical Science
bDivision of Respiratory Medicine, Shiga General Hospital
ABSTRACT
A 67-year-old man presenting with fever and cough was diagnosed with pneumonia caused by Legionella pneumophila, based on a combination of right-sided infiltrative shadows on chest radiography and a positive test for the Legionella urinary antigen. The patient’s condition rapidly deteriorated despite treatment with antibiotics, and he was transferred to our hospital. Although he had to be immediately intubated due to severe respiratory failure and septic shock on admission, he recovered completely after intensive treatment that included endotoxin adsorption with polymyxin B immobilized fiber column direct hemoperfusion and nitric oxide inhalation therapy. These intensive therapies could improve outcomes for patients with severe pneumonia caused by L. pneumophila.
KEYWORDS
Legionella pneumonia Endotoxin adsorption Nitric oxide inhalation
Received 26 Apr 2023 ／ Accepted 12 Jun 2023
AJRS, 12(5): 288-292, 2023
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