A case of drug-induced lung injury suspected to be due to Euglena gracilis
Koki Fukushimaa Sumako Yoshiokaa Toyomitsu Sawaia Nobuko Matsuoa Junichi Kadotaa Hiroshi Mukaeb
aDepartment of Respiratory Medicine, Nagasaki Harbor Medical Center
bDepartment of Respiratory Medicine, Nagasaki University Hospital
This case concerns a 48-year-old, male non-smoker who presented to our department with a chief complaint of dyspnea on exertion. Fever and hypoxemia were observed, and computed tomography showed diffuse ground-glass appearance and consolidation in all lung fields. Bronchoalveolar lavage showed an increased number of eosinophil, and a drug-induced lymphocyte stimulation test (DLST) was positive for Euglena gracilis (supplement), leading to the diagnosis of drug-induced lung injury. Euglena gracilis was discontinued, and methylprednisolone (mPSL) 1,000 mg/day for 3 days was administered. The clinical symptoms and laboratory findings rapidly improved.
Euglena gracilis Drug-induced lymphocyte stimulation test (DLST) Drug-induced lung injury
Received 8 Jun 2023 / Accepted 14 Jul 2023
AJRS, 12(5): 251-255, 2023