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Abstract
Case Report
Fatal fulminant community-acquired pneumonia due to hypervirulent Klebsiella pneumoniae
Hiroki Ebinaa Yuki Kondob Yasumasa Kunoc Masahide Inouec Shinichi Miyazakic Ryo Yamashitac
aDepartment of Internal Medicine, Yokkaichi Municipal Hospital
bDepartment of Respiratory Medicine, Nagoya University Graduate School of Medicine
cDepartment of Respiratory Medicine, Yokkaichi Municipal Hospital
ABSTRACT
A healthy 59-year-old man who had been experiencing right chest pain and dyspnea for two hours went to the emergency room. He had fever, hypoxemia, and right upper lobe consolidation on chest imaging. He received a diagnosis of community-acquired pneumonia (CAP). After hospitalization, his respiratory failure worsened rapidly, necessitating intubation and mechanical ventilation. After admission to the intensive care unit, he developed septic shock complicated by multiorgan failure. Despite supportive care (large volume fluid resuscitation, vasopressor therapy, and renal replacement therapy), he died 31 hours after presentation. Cultures of sputum and blood grew Klebsiella pneumoniae, and the string test was positive. Subsequently, based on genetic analyses, CAP induced by hypervirulent K. pneumoniae was diagnosed.
KEYWORDS
Community-acquired pneumonia (CAP) Hypervirulent Klebsiella pneumoniae Capsular serotype K2 Sequence type (ST) 86
Received 6 Jan 2023 ／ Accepted 12 May 2023
AJRS, 12(4): 205-209, 2023
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