Annals of The Japanese Respiratory Society:Biologic treatments in patients with allergic bronchopulmonary aspergillosis

Abstract

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Original Article

Biologic treatments in patients with allergic bronchopulmonary aspergillosis

Tomoya Maruyama^a Takashi Ishiguro^a Yotaro Takaku^a Ayako Yanagita^b Hideaki Sugita^b Tadashi Sannomiya^b Taisuke Isono^a Noboru Takayanagi^a

^aDepartment of Respiratory Medicine, Saitama Cardiovascular and Respiratory Center
^bDepartment of Pharmacy, Saitama Cardiovascular and Respiratory Center

ABSTRACT

We retrospectively investigated the efficacy of biologics in eight patients with allergic bronchopulmonary aspergillosis. All the patients had been treated with systemic corticosteroid therapy and antifungal agents, and biologics were radiologically effective in 54.5% of patients. In two of the three patients who had been treated with biologics for more than 1 year the beneficial effects were sustained.

KEYWORDS

Allergic bronchopulmonary mycosis (ABPM) Allergic bronchopulmonary aspergillosis (ABPA) Biologics Efficacy Eosinophil

Received 3 Dec 2022 ／ Accepted 7 Apr 2023

AJRS, 12(4): 179-185, 2023

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Original Article

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