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Article in Japanese
Abstract
Case Report
A case of refractory granulomatosis with polyangiitis that developed one month after coronavirus disease 2019 pneumonia had resolved without treatment
Ryo Haraa Taro Yonedaa Hayato Kobaa Tsukasa Uedaa Hiroko Moritaa Kazuyoshi Watanabeb
aDepartment of Respiratory Medicine, Komatsu Municipal Hospital
bDepartment of Respiratory Medicine, Japan Community Health Care Organization Kanazawa Hospital
ABSTRACT
A 65-year-old woman underwent a chest computed tomography scan that revealed infiltrative shadows on the right upper lobe and multiple nodules on the left upper and lower lobes, one month after she had suffered from a moderate case of coronavirus disease 2019 (COVID-19). Her blood tests were positive for myeloperoxidase anti-neutrophil cytoplasmic antibodies, and renal failure had developed. Renal biopsy revealed necrotizing and crescentic glomerulonephritis and she was therefore diagnosed with granulomatosis with polyangiitis. Rituximab treatment and steroid pulse therapy were initiated, which provided effective results. The onset of vasculitis after COVID-19 is not predictable from the disease severity of the COVID-19.
KEYWORDS
Coronavirus disease 2019 (COVID-19) Anti-neutrophil cytoplasmic antibody (ANCA) Granulomatosis with polyangiitis Crescentic glomerulonephritis
Received 14 Feb 2022 ／ Accepted 16 Feb 2023
AJRS, 12(3): 119-124, 2023
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