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Article in Japanese
Abstract
Case Report
A case of squamous cell lung carcinoma accompanied by lupus anticoagulant-hypoprothrombinemia syndrome
Yumi Ohiraa,b Yukihisa Inoueb Satoshi Endoc Hiroaki Takeyamab Nobuyuki Kondob Yasuto Jinnb
aDepartment of Respiratory Medicine, Yokosuka Kyosai Hospital
bDepartment of Respiratory Medicine, Hiratsuka Kyosai Hospital
cDepartment of Respiratory Medicine, Tokyo Medical and Dental University
ABSTRACT
A 65-year-old man was referred to our hospital because of cough and dyspnea on exertion. Chest computed tomography showed a mass on the left upper lobe. He was diagnosed with squamous cell lung carcinoma, cT4N3M1c Stage IVB. The laboratory findings revealed that prothrombin time (PT) and activated partial thromboplastin time (APTT) were prolonged. The lupus anticoagulant was identified and a decrease in prothrombin activity was observed. We reached a final diagnosis of lupus anticoagulant-hypoprothrombinemia syndrome (LAHPS). Prolongation of PT and APTT was correlated with the progression of squamous cell lung carcinoma under chemotherapy. Therefore, LAHPS as a paraneoplastic syndrome may be complicated by squamous cell lung carcinoma.
KEYWORDS
Lupus anticoagulant-hypoprothrombinemia syndrome (LAHPS) Squamous cell lung carcinoma Paraneoplastic syndrome (PNS)
Received 23 Feb 2022 ／ Accepted 4 Apr 2022
AJRS, 11(4): 183-187, 2022
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