A case of drug-induced pneumonitis caused by pharmaceutical additive agents
Juli Honda Toshihisa Ishikawa Reina Imase Kaori Okayasu Tsutomu Kawasaki
Department of Respiratory Medicine, Yokohama City Minato Red Cross Hospital
A 65-year-old man was referred to our department because of the appearance of ground glass opacities in the lower lobes of both lungs on chest CT. The shadows quickly disappeared when the aspirin/lansoprazole combination that had been recently started was discontinued. The drug-induced lymphocyte stimulation test (DLST) for aspirin/lansoprazole combination, aspirin, and lansoprazole tablets showed a response only for the combination tablet. Therefore, we suspected drug-induced pneumonitis brought about by the additive agents in the combination tablet. There are few reports of drug-induced pneumonitis caused by additive agents, so we report this case.
Drug-induced pneumonitis Additive agent Drug-induced lymphocyte stimulation test (DLST)
Received 23 Jun 2021 / Accepted 30 Aug 2021
AJRS, 10(6): 482-486, 2021