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Article in Japanese
Abstract
Case Report
COVID-19-associated pulmonary aspergillosis: a case report
Yusuke Mori Naoto Kubo Yu Isoshima Yasuhiko Nikaido Teppei Hoshino
Department of Respiratory Medicine, Kitakyushu City Yahata Hospital
ABSTRACT
A 76-year-old man was admitted to our hospital due to coronavirus disease 2019 (COVID-19). He eventually required intubation and mechanical ventilation due to progressive respiratory failure. A chest computed tomography (CT) scan, performed 14 days following the onset of symptoms, revealed a mass-like consolidation with surrounding ground-glass opacities in the lingular region of the left lung. He was diagnosed with COVID-19-associated pulmonary aspergillosis (CAPA) following a positive sputum culture and high serum antigen titer of Aspergillus fumigatus. Despite treatment with antifungal drugs, the patient died on day 43. Diagnosis and treatment of CAPA among intensive care unit patients is often challenging. Given the high mortality rate of CAPA, we should be aware of the possibility of this secondary infection in patients with severe COVID-19.
KEYWORDS
Coronavirus disease 2019 (COVID-19) COVID-19-associated pulmonary aspergillosis (CAPA) Invasive pulmonary aspergillosis (IPA)
Received 3 Jun 2021 ／ Accepted 21 Sep 2021
AJRS, 10(6): 472-476, 2021
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