A case of anti-ARS antibody-positive interstitial pneumonia with eosinophilia in bronchoalveolar lavage fluid
Hideto Oshita Tatsuki Takahashi Misato Senoo Kunihiko Funaishi Yasuyuki Mitama Ken Okusaki
Department of Internal Medicine, Mihara Medical Association Hospital
A 66-year-old woman complained of dyspnea on exertion. Her chest CT showed ground-glass opacities on bilateral lower lobes, suggesting nonspecific interstitial pneumonia. She showed mechanic's hand and was positive for serum anti-aminoacyl tRNA synthetase (anti-ARS) antibody. Bronchoscopy revealed eosinophilia (30%) in the bronchoalveolar lavage fluid; thus, eosinophilic pneumonia needed to be ruled out. The bilateral lung shadows disappeared when prednisolone was commenced. Since anti-ARS antibody-positive interstitial pneumonia may show eosinophilia in bronchoalveolar lavage fluid, it is necessary to carefully distinguish it from eosinophilic pneumonia via image findings and physical examination.
Anti-aminoacyl tRNA synthetase (ARS) antibody Bronchoalveolar lavage fluid (BALF) Eosinophilic pneumonia
Received 2 Sep 2020 / Accepted 9 Oct 2020
AJRS, 10(1): 74-77, 2021