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Article in Japanese
Abstract
Case Report
Short-term treatment with systemic steroids in moderate coronavirus infectious disease 2019: a case report and review of domestic cases
Kentaro Fukunagaa Yasuki Uchidab Yasushi Omuraa Yuki Yagia Daisuke Kinoseb Masafumi Yamaguchib
aDepartment of Internal Medicine, Kohka Public Hospital
bDivision of Respiratory Medicine, Department of Internal Medicine,Shiga University of Medical Science
ABSTRACT
Effective treatment for coronavirus infectious disease 2019 has not yet been established. Infection with severe acute respiratory syndrome coronavirus 2 induces hypercytokinemia. Consequently, patients may develop pneumonia and, in severe cases, acute respiratory distress syndrome. Therefore, it is necessary to develop a therapeutic strategy to suppress inflammatory cytokines. Two of our patients showed aggravated symptoms despite the use of antiviral drugs. Short-term treatment with systemic steroids in the moderate phase improved their condition. Similar results have been reported in other cases in Japan and other countries. It is necessary to consider short-term treatment with systemic steroids along with antiviral drugs in the event of poor response to antiviral drugs and hypoxia.
KEYWORDS
Coronavirus infectious disease 2019 (COVID-19) Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Viral pneumonia Systemic steroid
Received 2 Jun 2020 ／ Accepted 4 Aug 2020
AJRS, 9(6): 432-437, 2020
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