A case of eosinophilic granulomatosis with polyangiitis with subarachnoid hemorrhage as the first manifestation
Yui Narasakia Yusuke Takayamab Erika Kobayashic Takashi Nakamurad Ken Masudab Hiroyasu Shodab
aDepartment of Internal Medicine, Hiroshima City Medical Association-administered Hiroshima City Aki Hospital
bDepartment of Respiratory Medicine, Hiroshima City Hiroshima Citizens Hospital
cDepartment of Respiratory Medicine, Miyoshi Central Hospital
dDepartment of Respiratory Medicine, JA Hiroshima General Hospital
A 57-year-old man, who had a long history of asthma, and had been treated with prednisolone (PSL) for chronic eosinophilic pneumonia for 3 years, was admitted to our hospital because of severe headache and disturbance of consciousness. He was diagnosed with subarachnoid hemorrhage (SAH), and then treated with coil embolization. However, 3 months after SAH onset, he noticed purpura on the lower legs and numbness in the extremities. At the same time, peripheral blood eosinophilia progressed gradually. Six months after SAH onset, he was diagnosed with eosinophilic granulomatosis with polyangiitis (EGPA). It is necessary to pay careful attention to SAH as a first clinical manifestation of EGPA.
Eosinophilic granulomatosis with polyangiitis (EGPA) Subarachnoid hemorrhage (SAH) Cerebral aneurysm Peripheral blood eosinophilia
Received 28 Feb 2020 / Accepted 23 Apr 2020
AJRS, 9(4): 294-298, 2020