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Abstract
Case Report
A case of amyloid light-chain amyloidosis associated with rheumatoid arthritis
Satoru Miwaa,＊ Fumiaki Katoa Megumi Katsumataa Wataru Matsuyamaa Norio Kasamatsua Takafumi Sudab
aDepartment of Respiratory Medicine, Hamamatsu Medical Center
bSecond Division, Department of Internal Medicine, Hamamatsu University School of Medicine
＊Present address: Departments of Hospice, Seirei Mikatahara General Hospital
ABSTRACT
A 70-year-old woman who was undergoing prednisolone treatment for rheumatoid arthritis-associated interstitial lung disease visited our hospital because of dyspnea on exertion. Chest unenhanced computed tomography revealed pericardial effusion, pleural effusion, and enlarged axillary and mediastinal lymph nodes. The axillary lymph node biopsy demonstrated amyloid A (AA)-negative amyloidosis. Based on the concomitant increase in serum IgG-λ type free light chain, we diagnosed her with amyloid light-chain (AL) amyloidosis in association with rheumatoid arthritis. We report this rare case of AL amyloidosis associated with rheumatoid arthritis.
KEYWORDS
Rheumatoid arthritis (RA) Amyloid A (AA)-negative amyloidosis Amyloid light-chain (AL) amyloidosis
Received 15 Oct 2019 ／ Accepted 9 Jan 2020
AJRS, 9(3): 217-221, 2020
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