A case of severe pneumonia caused by Panton-Valentine leukocidin-producing community-acquired MRSA in a healthy adult
Satoshi Mikami Yasushi Makino Syunsaku Hayai Takaaki Kasahara
Department of Respiratory Medicine, Chutoen General Medical Center
A 56-year-old man presented to our hospital with complaints of a high fever and cough. Chest X-ray and computed tomography showed right upper lobe pneumonia, and the patient was admitted. Several days after admission, the patient’s respiratory function deteriorated rapidly, with expansion of pulmonary consolidation and destruction of pulmonary structures. The patient was transferred to the intensive care unit for intubation and mechanical ventilation. A sputum culture on admission identified methicillin-resistant Staphylococcus aureus (MRSA), which was positive for the gene encoding Panton-Valentine leukocidin (PVL), a leukocytoclastic toxin. The patient survived and was discharged following administration of anti-MRSA agents and intensive care. He was diagnosed with PVL-producing community-acquired MRSA (CA-MRSA) pneumonia, which is considered rare in Japan.
Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) Severe pneumonia
Received 16 Jul 2019 / Accepted 26 Sep 2019
AJRS, 9(1): 18-22, 2020