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Article in Japanese
Abstract
Case Report
A case of nivolumab-associated autoimmune encephalitis
Osamu Honjo Toyohiro Saikai Hiroyuki Koba
Department of Pulmonary Diseases, Sapporo Minami-Sanjo Hospital
ABSTRACT
A 59-year-old man received 22 courses of nivolumab as second-line therapy for large cell carcinoma of the lung, clinical stage IIIA. He was admitted to our hospital due to alteration of consciousness. We diagnosed autoimmune encephalitis and treated him with corticosteroids. This resulted in an improvement of neurological symptoms with no sequelae. Early steroid administration should be considered to treat autoimmune encephalitis developed during nivolumab therapy.
KEYWORDS
Nivolumab Non small cell lung cancer Immune-related adverse event Autoimmune encephalitis
Received 29 Aug 2018 ／ Accepted 28 Feb 2019
AJRS, 8(3): 167-172, 2019
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