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Abstract
Case Report
A case of lansoprazole-induced lung injury
Isao Hasegawaa Takatoyo Kambayashib Hisataka Tsushimac
aDepartment of Pulmonary Medicine, Japanese Red Cross Kyoto Daini Hospital
bHouse Call Center, Kyoto Min-iren Daini, Chuo Hospital
cDepartment of Internal Medicine, Kyoto Johnan Clinic
ABSTRACT
A 63-year-old male had an operation for duodenal cancer and lansoprazole was prescribed. About two months later, he was admitted to Kyoto Min-iren Chuo Hospital due to dry cough and shortness of breath. Chest CT images revealed ground glass opacification in both upper lung lobes. On the basis of physical examinations and test results, drug-induced lung injury was suspected. Bronchoalveolar lavage fluid (BALF) showed markedly increased lymphocytes. In addition to these results, a drug lymphocyte stimulating test (DLST) for lansoprazole showed positive. Based on these findings, the patient was diagnosed with lansoprazole-induced lung injury. This case shows that although lansoprazole is frequently used and a relatively safe medication that rarely causes drug-induced lung injury, we should nonetheless bear this possibility in mind.
KEYWORDS
Lansoprazole Drug-induced lung injury Bronchoalveolar lavage fluid (BALF) Drug lymphocyte stimulating test (DLST)
Received 14 Jun 2018 ／ Accepted 10 Oct 2018
AJRS, 8(1): 47-51, 2019
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