A case of a ruptured peripheral pulmonary artery aneurysm in a patient taking edoxaban, a factor Xa inhibitor
Hikaru Mamizu Aya Ohtsubo Tomohiro Tanaka Takeshi Ohta Toshiki Furukawa Takashi Ishida
Department of Respiratory Medicine, Niigata Prefectural Central Hospital
An 80-year-old man with a history of taking edoxaban for 1 year presented with ground-glass opacity in the right lower lung field on chest radiograph at his regular checkup, although he was asymptomatic at that time. One week later, he was referred to our hospital with hemoptysis. Chest contrast-enhanced computed tomography images showed a nodule in the middle lobe of the right lung. Furthermore, selective bronchial angiography revealed an aneurysm with a diameter of approximately 13mm in the right lower lung field. Therefore, a diagnosis of a ruptured pulmonary aneurysm was confirmed. The anticoagulant might have caused the pulmonary artery aneurysm to rupture, but because the risk of hemorrhagic diathesis is low with factor Xa inhibitors, it had restricted the speed and volume of the bleeding after the rupture.
Edoxaban Pulmonary artery aneurysm Hemoptysis
Received 9 Mar 2018 / Accepted 28 Jun 2018
AJRS, 7(5): 338-341, 2018