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Abstract
Case Report
Two cases of advanced non-small cell lung cancer on hemodialysis treated with pembrolizumab
Katsuaki Yazawaa Masahumi Doib Hiroki Ikurab Mayumi Fujiib Yoshikazu Tsukadab
aDepartment of Pulmonary Medicine, Ome Municipal General Hospital
bDepartment of Pulmonary Medicine, Soka Municipal Hospital
ABSTRACT
Case 1: A 70-year-old male with end-stage renal disease (ESRD) on hemodialysis was referred to our hospital with abnormal right upper lobe shadowing on chest X-ray. He was diagnosed with stage IIIB squamous cell carcinoma (tumor proportion score: 50%‒60%). Pembrolizumab was administered ten times and tolerated. Case 2: A 79-year-old male with ESRD on hemodialysis was referred to our hospital with abnormal right middle lobe shadowing on chest X-ray. He was diagnosed with stage IIIA adenocarcinoma (tumor proportion score: 50%‒74%). Pembrolizumab was administered. A cerebral infarction occurred after a few days and pembrolizumab was withdrawn. Pembrolizumab can be considered as a treatment option in non-small cell lung cancer patients with ESRD on hemodialysis.
KEYWORDS
Chronic kidney disease Hemodialysis Non-small cell lung cancer Anti PD-1 antibody Pembrolizumab
Received 22 Feb 2018 ／ Accepted 12 Jun 2018
AJRS, 7(5): 306-310, 2018
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