A case of localized pulmonary granulomatosis with polyangiitis presenting as a solitary tumor
Koji Tokudaa Naomi Kuroudua Oji Obayashia Tamiko Takemurab Yukihiko Sugiyamaa
aDepartment of Pulmonary Medicine, Nerima Hikarigaoka Hospital
bDepartment of Pathology, Japanese Red Cross Medical Center
A 67-year-old female was referred to our hospital with an abnormal shadow on chest X-ray. Chest-computed tomography scan revealed a solitary mass shadow in the left lower lobe. As fibrobronchoscopy did not lead to a diagnosis, video-assisted thoracic surgery was performed. Pathological findings showed microabscess, palisading granuloma, and necrotic granulomatous angiitis. The patient was diagnosed with granulomatosis with polyangiitis (GPA). The illness has had an uneventful course without any treatment for more than 1 year. Although cases of solitary lung lesions have rarely been reported, it is important to take GPA into consideration as one of the differential diagnoses for the solitary nodule. This case also demonstrates the diverse disease activity of GPA.
Granulomatosis with polyangiitis Solitary tumor Video-assisted thoracic surgery Palisading granuloma
Received 20 Nov 2017 / Accepted 5 Feb 2018
AJRS, 7(3): 156-160, 2018