Leiomyosarcoma revealed by re-biopsy in a patient with neuroendocrine carcinoma of the lung receiving chemotherapy: a case report
Satoru Kawashimaa Yusuke Shiraishib Satoshi Marumob Takafumi Nishimurac Yoshiaki Yubad Motonari Fukuib
aDepartment of Respiratory Medicine, Shiga University of Medical Science Hospital
bDepartment of Respiratory Disease Center, Kitano Hospital, Tazuke Kofukai Medical Research Institute
cDepartment of Medical Oncology, Kitano Hospital, Tazuke Kofukai Medical Research Institute
dDepartment of Diagnostic Pathology, Kitano Hospital, Tazuke Kofukai Medical Research Institute
A 67-year-old man visited our hospital complaining of cough, dyspnea, and left chest discomfort. Chest contrast-enhanced computed tomography (CT) scans showed multiple tumors in the pleura and pleural effusions in the left thorax. He was diagnosed with neuroendocrine carcinoma based on cell block analysis of the pleural effusion. He received several chemotherapeutic regimens for small cell lung carcinoma. As some atypical findings for neuroendocrine carcinoma were detected, such as tumor localization in the left pleura, a CT-guided fine needle biopsy was performed on one of the tumors in his left thorax, resulting in a diagnosis of leiomyosarcoma. Thereafter, he received chemotherapy for leiomyosarcoma. Re-biopsy should be considered when patients with lung cancer exhibit atypical clinical findings.
Neuroendocrine carcinoma Leiomyosarcoma Re-biopsy
Received 6 Nov 2017 / Accepted 6 Mar 2018
AJRS, 7(3): 151-155, 2018