Annals of The Japanese Respiratory Society:Talc pleurodesis for patients with malignant pleural effusion

Vol.7 No.3 Table of Contents

Abstract

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Article in Japanese

Original Article

Talc pleurodesis for patients with malignant pleural effusion

Hiroshi Yaginuma^a Shinichi Kawana^a Mao Yoshikawa^a Hisao Mizutani^b

^aDepartment of Respiratory Medicine, Ako Central Hospital
^bDepartment of Thoracic Surgery, Himeji Red Cross Hospital

ABSTRACT

In Japan, only a few studies have been conducted on talc pleurodesis. We evaluated the efficacy, safety, and risk factors for treatment failure of talc pleurodesis in 22 patients who underwent talc pleurodesis at our hospital from January 2014. Of the 22 patients, treatment was effective in 10 patients (45%). Fourteen (64%) developed adverse events, but serious adverse events were not observed. Efficacy was significantly lower in the group with poor performance status (PS) and serum C-reactive protein (CRP) levels of ≥1.0 mg/dL (p=0.002 and p=0.020, respectively). PS and serum CRP are indicated as risk factors for talc pleurodesis failure.

KEYWORDS

Malignant pleural effusion Pleurodesis Talc

Received 19 Dec 2017 ／ Accepted 23 Feb 2018

AJRS, 7(3): 131-134, 2018

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