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Article in Japanese
Abstract
Case Report
Primary lung adenocarcinoma associated with IgG4-related lung disease
Koji Tokudaa,b Takakiyo Nakayab Masayuki Nakayamab Masashi Bandob Yukihiko Sugiyamab Hirokazu Hagiwarab
aRespiratory and COPD Center, Japan Association for Development of Community Medicine Nerima Hikarigaoka Hospital
bDivision of Pulmonary Medicine, Department of Medicine, Jichi Medical University
ABSTRACT
IgG4-related lung disease was diagnosed in a 71-year-old man, and resolved spontaneously. However, five years later, a chest contrast-enhanced computed tomography (CT) scan showed bilateral lung nodules, and hilar and mediastinal lymphadenopathy. His serum IgG4 levels were elevated. Based on the diagnosis of a recurrence of IgG4-related lung disease, systemic corticosteroid therapy was introduced. Chest radiologic findings improved and serum IgG4 levels declined. Subsequently, however, a right hilar mass and mediastinal lymphadenopathy appeared on chest contrast-enhanced CT scan. A transbronchial biopsy specimen obtained from the right main bronchus revealed primary lung adenocarcinoma. Physicians should be aware that primary lung cancer might be associated with IgG4-related lung disease.
KEYWORDS
IgG4-related lung disease Primary lung adenocarcinoma Transbronchial biopsy
Received 21 Jul 2017 ／ Accepted 1 Nov 2017
AJRS, 7(1): 20-24, 2018
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