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Article in Japanese
Abstract
Case Report
A case of multiple system atrophy diagnosed following acute hypercapnic respiratory failure
Tomoyo Taketaa Miho Suginakab Koichi Furukawab Naoki Nakamurab Takao Kamimorib Hiroshi Fujiwarab
aDepartment of Respiratory Medicine, Hoshigaoka Medical Center
bDepartment of Respiratory Medicine, Yodogawa Christian Hospital
ABSTRACT
A 67-year-old woman with interstitial pneumonia underwent portable monitoring because sleep apnea syndrome was suspected due to snoring. Results showed an apnea-hypopnea index (AHI) of 40.2/hr. We administered nasal continuous positive airway pressure, but the resulting improvement in AHI was insufficient. Overnight polysomnography demonstrated hypoventilation with severe hypoxia. She subsequently complained of bilateral leg weakness and hoarseness that was suspected to be due to a neuromuscular disorder, but we could not make a definitive diagnosis. While under observation, she suddenly developed acute hypercapnic respiratory failure, and we finally diagnosed her with multiple system atrophy (MSA). We report this case here because MSA initially presenting with hypoventilation that culminates in acute hypercapnic respiratory failure is rare.
KEYWORDS
Multiple system atrophy Acute hypercapnic respiratory failure Polysomnography
Received 23 Mar 2017 ／ Accepted 26 Jul 2017
AJRS, 6(6): 483-487, 2017
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