A case of nonislet cell tumor hypoglycemia with lethargy caused by a solitary fibrous tumor of the pleura
Sayaka Inouea Koji Tamaia Daiki Masuyaa Yuko Koketsub Kazuhito Ichikawac Yujiro Suzukia
aDepartment of Respiratory Medicine, Shinko Hospital
bDiabetes Metabolism Internal Medicine, Shinko Hospital
cPathology Diagnostic Center, Shinko Hospital
A 72-year-old male was admitted to our hospital presenting with dyspnea, disorientation, and lethargy over the past seven months. Chest computed tomography (CT) revealed the presence of a large tumor in the left thoracic cavity. Refractory hypoglycemia and a low insulin level were also found. A suspected solitary fibrous tumor of the pleura was revealed by CT-guided percutaneous needle biopsy; we therefore speculated that the patient had developed nonislet cell tumor hypoglycemia due to a solitary fibrous tumor of the pleura. After surgical resection of the tumor, the hypoglycemia disappeared. We diagnosed a solitary fibrous tumor of the pleura on pathologic evaluation of the resected tumor. A high molecular weight form of insulin-like growth factor II was detected in the patient’s serum preoperatively, but not postoperatively.
Solitary fibrous tumor Pleura Nonislet cell tumor hypoglycemia Surgery High molecular weight form of IGF-Ⅱ
Received 26 Mar 2017 / Accepted 10 Aug 2017
AJRS, 6(6): 454-457, 2017