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Article in Japanese
Abstract
Original Article
Assesment of environmental risk factors for nontuberculousis mycobacteria disease in southern Ibaraki Prefecture in Japan
Yuka Mishimaa,b Tomoyuki Ogatab Hiroaki Kobayashib Reina Imaseb Tamon Yagib,d Hiroaki Saitoc,d Takaaki Yamashitab,c Kazuhito Saitoc Toshihide Fujied Naohiko Inased
aDepartment of Respiratory Medicine, Ome Municipal General Hospital
bDepartment of Respiratory Medicine, JA Toride Medical Center
cDepartment of Respiratory Medicine, Tsuchiura Kyodo General Hospital
dDepartment of Respiratory Medicine, Tokyo Medical and Dental University
ABSTRACT
Nontuberculous mycobacteria (NTM) inhabit human living environments, especially in soil and water. We examined the effect of exposure to soil and well water usage on Mycobacterium avium-intracellulare complex (MAC) infection in southern Ibaraki Prefecture. In 128 patients with MAC pulmonary disease (30 men, 98 women, 69.6±9.4 years), 26 patients (20%) were exposed to soil more than twice a week, 10 patients (8%) used well water, and 22 patients (17%) experienced both. Mycobacterium intracellulare were frequently detected from patients with exposure to soil and well water usage. Multivariate analysis showed that exposure to soil (odds ratio 3.09, p=0.016) was an independent risk factor of M. intracellulare infection, and the odds ratio of well water usage was 2.48 (p=0.073).
KEYWORDS
Non-tuberculous mycobacteria Soil exposure Well water
Received 4 Jun 2016 ／ Accepted 6 Jan 2017
AJRS, 6(3): 129-135, 2017
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