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Abstract
Case Report
A case of pulmonary Mycobacterium xenopi infection diagnosed by 16S rRNA gene sequencing
Naoko Aranoa Mitsuaki Sekiyaa Kenji Suzukib Toshimasa Uekusac Ken Kikuchid Kazuhisa Takahashia
aDepartment of Respiratory Medicine, Internal Medicine, Faculty of Medicine, Juntendo University
bDepartment of General Thoracic Surgery, Faculty of Medicine, Juntendo University
cDepartment of Diagnostic Pathology, Kanto-Rosai Hospital
dDepartment of Infectious Diseases, Tokyo Medical Women's University
ABSTRACT
A 47-year-old woman was referred to our hospital because of a nodular lesion at the left upper lobe. She underwent a left upper partial lobectomy and positive findings of an acid-fast bacterium (AFB) smear test were detected, which suggested a pulmonary mycobacterium infection. However, polymerase chain reaction identification for Mycobacterium tuberculosis and Mycobacterium avium complex was negative. Culture for 8 weeks was also negative for AFB. We then performed a 16S rRNA gene sequence for using formalin-fixed, paraffin-embedded lung tissue and finally diagnosed as a Mycobacterium xenopi infection.
KEYWORDS
Mycobacterium xenopi Pulmonary nontuberculous mycobacteriosis
Received 3 Apr 2016 ／ Accepted 14 Nov 2016
AJRS, 6(2): 89-94, 2017
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