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Abstract

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Article in Japanese

Case Report

A rare and cured case of pulmonary mucormycosis triggered by exacerbation of COPD with bronchial asthma and diagnosed by sputum culture

Tomohisa Okamotoa  Kimitaka Akaikeb  Hajime Iwagoec  Hiroto Kishia  Koichiro Fukudaa 

aDepartment of Respiratory Medicine, Kumamoto City Hospital
bDepartment of Respiratory Medicine, Kumamoto University Hospital
cDepartment of Infectious Disease, Kumamoto City Hospital

ABSTRACT

An 82-year-old man presented a bilateral infiltrating shadow on chest X-ray in the course of treatment with antibiotics and steroids for exacerbation of chronic obstructive pulmonary disease (COPD) with bronchial asthma. A diagnosis of pulmonary mucormycosis was established because we confirmed the sporangium in the sputum culture colony, which is characteristic of Mucorales. He recovered by treatment with liposomal amphotericin B and was then transferred to another hospital for rehabilitation. Mucormycosis is an opportunistic infectious disease seen in cases with hematologic malignancy, neutropenia, and immunosuppressive drugs including steroids and deferoxamine therapy. Mucormycosis usually shows poor prognosis in medical therapy. We report here a rare recovered case of pulmonary mucormycosis in which sputum culture contributed early diagnosis.

KEYWORDS

Mucormycosis  Fungal infection  Immunosuppression  Liposomal amphotericin B 

Received 1 Jul 2016 / Accepted 3 Aug 2016

AJRS, 5(6): 346-350, 2016

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