Two cases with chronic progressive pulmonary aspergillosis after thoracic irradiation for non-small cell lung cancer
Hiroshi Ueno Takuro Sakagami Yasuyoshi Oshima Satashi Watanabe Hiroshi Moro Toshiaki Kikuchi
Department of Respiratory Medicine and Infectious Disease, Niigata University Medical and Dental Hospital
A 75-year-old man and a 64-year-old man were administered with corticosteroids for irradiation pneumonia after irradiation therapy for recurrent non-small cell lung cancer. Their infiltrate shadow then progressed rapidly. Invasive pulmonary aspergillosis was diagnosed and treated with antifungal agents. In such cases, immunosuppressive therapy may lead to life-threatening exacerbation of systemic fungal infection. We need to consider the possibility of Aspergillus infection in subjects with underlying lung disease.
Chronic progressive pulmonary aspergillosis Lung cancer Irradiation pneumonitis Underlying pulmonary disease Steroid
Received 20 Jun 2016 / Accepted 5 Aug 2016
AJRS, 5(6): 341-345, 2016