A case of pulmonary tumor embolism caused by extramammary Paget's disease whose tumor cells were proven by pulmonary wedge aspiration cytology
Wakako Shinoharaa Noboru Takayanagia Takashi Ishiguroa Naho Kagiyamaa Yoshihiko Shimizub Yutaka Sugitaa
aDepartment of Respiratory Medicine, Saitama Cardiovascular and Respiratory Center
bDepartment of Pathological Diagnosis, Saitama Cardiovascular and Respiratory Center
The patient was a 75-year-old male. Three years earlier eruptions appeared in the vulva but were left untreated. The patient became aware of shortness of breath ten days ago and visited our hospital for examination. The SpO2 was 79%, and a chest CT revealed ground-glass opacity in part of the right lower lobe. Right ventricular systolic pressure was estimated at 65 mmHg by echocardiography, and lung perfusion scintigraphy showed perfusion defect in the periphery of both lungs. Suspecting pulmonary arterial tumor embolism, we performed pulmonary wedge aspiration cytology and detected tumor cells. Extramammary Paget's disease was diagnosed, based on a skin biopsy of the external genitalia. This matched the findings of the pulmonary wedge aspiration cytology, so the case was diagnosed as pulmonary arterial tumor embolism caused by extramammary Paget's disease.
Pulmonary tumor embolism Pulmonary wedge aspiration cytology Pulmonary hypertension Acute respiratory failure Malignant tumor
Received 13 Feb 2016 / Accepted 28 Jun 2016
AJRS, 5(6): 302-306, 2016