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Article in Japanese
Abstract
Case Report
Anti-EJ antibody positive polymyositis-associated interstitial pneumonia: A case report
Fumika Uenoa Mari Yokozekia Fukue Ishizua Mariko Ikedaa Takeshi Ueharab Takashige Miyaharaa
aDepartment of Respiratory Medicine, Nagano Matsushiro General Hospital
bDepartment of Laboratory Medicine, Shinshu University School of Medicine
ABSTRACT
A 66-year-old woman visited our hospital because of abnormal chest radiograph on a health checkup, which shows bilateral consolidation, reticular shadow, and volume loss. On physical examination, she had exertional dyspnea, pain in the left knee joint, muscle weakness of limbs, and keratinization of fingers and thumbs. She was pathologically diagnosed with myositis accompanied by interstitial pneumonia. Her serological examination revealed she has anti-EJ antibody, among anti-aminoacyl tRNA synthetase (ARS) antibodies. Her symptoms and lung lesions have improved by combination therapy of corticosteroid and immunosuppressant. We suggest that anti-ARS antibody is very useful to make a diagnosis and perhaps to predict a prognosis.
KEYWORDS
Anti-aminoacyl-tRNA synthetase antibodies Anti-EJ antibodies Interstitial pneumonia Polymyositis Dermatomyositis
Received 17 Dec 2015 ／ Accepted 27 Apr 2016
AJRS, 5(5): 250-254, 2016
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