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Abstract
Diagnostic Imaging
A case of AIDS-related Pneumocystis jirovecii pneumonia with multiple cystic and nodular lesions
Risa Watanabe Eri Iwami Shinnosuke Ikemura Takahiro Nakajima Tatsu Matsuzaki Takeshi Terashima
Department of Respiratory Medicine, Tokyo Dental College Ichikawa General Hospital
ABSTRACT
A 40-year-old homosexual man presented with cough and progressive respiratory distress for 6 months. Initially, chest X-ray showed cystic lesion in the left upper lung. A computed tomography scan revealed multiple cystic and nodular lesions in both lungs. He was diagnosed as AIDS-related Pneumocystis jirovecii pneumonia based on HIV infection, elevated levels of KL-6 and β-D-glucan, decreased level of CD4-positive T lymphocytes, and positive detection of P. jirovecii DNA by polymerase chain reaction in bronchoalveolar lavage fluid. Regression of cystic and nodular lesions was achieved after sulfamethoxazole-trimethoprim and atovaquone therapy. This case showed radiologically unique findings of AIDS-related P. jirovecii pneumonia with multiple cystic and nodular lesions.
KEYWORDS
Pneumocystis pneumonia AIDS Cystic lesion Nodular opacity
Received 14 Feb 2016 ／ Accepted 23 Mar 2016
AJRS, 5(4): 230-233, 2016
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