Pulmonary nocardiosis resulting from Nocardia abscessus in a patient with bronchiectasis
Yasuteru Suginoa Shunichi Takia Ryo Sandaa Motohiro Kimuraa Yasuyuki Takagia Saki Katob
aDepartment of Respiratory Medicine, Toyota Memorial Hospital
bDepartment of Internal Medicine, Toyota Memorial Hospital
A 66-year-old woman with bronchiectasis, who complained of fever and bloody sputum, was found by chest CT to have multiple cavity shadows in the right-lower lung lobe and also small centrilobular nodules in the bilateral lung fields on bronchiectatic findings. Nocardia was detected three times in the sputum culture test, diagnosed with pulmonary nocardiosis. A switch to the sulfamethoxazole-trimethoprim from the initial treatment of meropenem showed the improvement of symptoms, blood inflammatory data, and chest imaging findings. Nocardia abscessus was identified by 16S rRNA gene analysis. In the future, N. abscessus also needs to be regarded as a pathogen of pulmonary nocardiosis in Japan.
Bronchiectasis Pulmonary nocardiosis Nocardia abscessus 16S rRNA Antimicrobial susceptibilities
Received 26 Aug 2015 / Accepted 22 Oct 2015
AJRS, 5(2): 96-100, 2016