A rare case of metastatic leiomyosarcoma showing favorable response to combination chemotherapy
Tomoharu Matsuia,b Tomoki Fujiia,b Nami Hasegawab Hironobu Yasuyamab Naohi Saharaa,b Seiji Irieb
aDepartment of Oncology, Japan Labour, Health and Welfare Organization
bDepartment of Hematology, Japan Labour, Health and Welfare Organization
Although a metastatic or recurrent soft tissue sarcoma is less sensitive to cytotoxic chemotherapeutic agents, the standard therapy for this disease is systemic chemotherapy. A 66-year-old man showed multiple metastases after resection of leiomyosarcoma of the left limb (pT1bN0M0G1, stage IA). Among them was endobronchial metastasis, which caused left atelectasis and obstructive pneumonia. We experienced a rare case of metastatic leiomyosarcoma showing favorable response to combination chemotherapy with doxorubicin and ifosfamide, which allows for effective endobronchial management.
Leiomyosarcoma Endobronchial metastasis Combination chemotherapy
Received 13 Aug 2015 / Accepted 2 Dec 2015
AJRS, 5(2): 80-83, 2016