A case of Trousseau syndrome associated with squamous cell lung cancer
Ryota Aoki Kosuke Kashiwabara Shinji Fujii Shinsuke Tsumura Hiroshi Semba
Department of Respiratory Medicine, Kumamoto Regional Medical Center
An 84-year-old man with pulmonary squamous cell carcinoma (cT1bN3M1a; stage IV) in the left upper lobe, and the carcinomatous pleurisy received talc pleurodesis. He had a sudden onset of hemiplegia before the initiation of anticancer chemotherapy. A brain MRI test showed multiple high-intensity signals in the right cerebellar hemisphere and both sides of cerebral cortex. Although there were no other risk factors for hypercoagulation, brain infarctions continued to deteriorate under anticoagulant therapy. He was diagnosed as having Trousseau syndrome associated with primary lung cancer. An additional anticancer therapy (tegafur-gimeracil-oteracil potassium 80 mg/body) did not improve his condition, and he died of aspiration pneumonia on hospital day 20. We report a rare case of Trousseau syndrome occurring in patients with pulmonary squamous cell carcinoma.
Trousseau syndrome Cerebral thrombosis Squamous cell lung cancer
Received 6 Jun 2015 / Accepted 24 Sep 2015
AJRS, 5(1): 3-7, 2016