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Article in Japanese
Abstract
Case Report
A case of hypereosinophilic syndrome with eosinophilic infiltration, pulmonary thromboembolism, and deep venous thrombosis
Seishi Higashia,b Youko Suzukib Naoki Nishiyamab,c Wataru Ejimab Rinako Yamashitab Reiko Takib
aDivision of Respiratory Medicine, Tokyo Medical and Dental University
bDivision of Respiratory Medicine, Musashino Red Cross Hospital
cDivision of Respiratory Medicine, Tsuchiura Kyodo General Hospital
ABSTRACT
A 55-year-old man presented with high fever and dyspnea. A chest X-ray and a chest CT scan showed diffuse infiltration in both lungs, and laboratory findings revealed severe eosinophilia in both peripheral blood and bronchoalveolar lavage fluid (BALF). Further examinations led to a diagnosis of hypereosinophilic syndrome (HES) with disseminated intravascular coagulation (DIC). Corticosteroid therapy rapidly reduced eosinophilia and pulmonary infiltration, but the DIC stage remained, suggesting that thromboembolism was complicated. The postcontrast CT scan showed pulmonary thromboembolism and deep venous thrombosis, which were successfully treated with warfarin. Interestingly, on CT scans we could distinguish consolidations of pulmonary infarction from diffuse eosinophilic infiltration.
KEYWORDS
Hypereosinophilic syndrome Pulmonary thromboembolism DIC
Received 14 Jun 2014 ／ Accepted 20 Oct 2014
AJRS, 4(1): 86-90, 2015
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