The most common causes of chronic coughs with normal chest radiograph and pulmonary function test findings include cough variant asthma (CVA), gastroesophageal reflux disease (GERD), upper airway cough syndrome (UACS), postnasal drip syndrome (PNDS), and the use of angiotensin converting enzyme (ACE) inhibitors. Although the current diagnostic and treatment guidelines for chronic cough attempt to rule out such conditions, a significant proportion of chronic coughs remain unexplained. In recently reported cases of chronic cough in which obstructive sleep apnea syndrome (OSAS) was concomitantly diagnosed, continuous positive airway pressure (CPAP) therapy was found to improve the patients' coughs. Although the current guidelines for chronic cough include no tests for the diagnosis of OSAS, this disease is increasingly being recognized as a cause of chronic cough. This review describes clinical evidence of chronic cough associated with OSAS and the usefulness of CPAP for the management of OSAS-induced chronic cough.