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Abstract
Case Report
Four cases of invasive thymoma accompanied by polymyositis, presenting respiratory dysfunction
Kenichiro Shimizua Nayuta Saitoa Shusaku Omotob Toru Haradac Makoto Kawaishia Kazuyoshi Kuwanoa
aDivision of Respiratory Medicine, Department of Internal Medicine, The Jikei University School of Medicine
bDivision of Neurology, Department of Internal Medicine, The Jikei University School of Medicine
cDepartment of Pathology, The Jikei University School of Medicine
ABSTRACT
Thymoma is accompanied by a variety of paraneoplastic syndromes, such as MG. However, polymyositis (PM) is rare. Here we have experienced four cases of invasive thymoma accompanied with PM, presenting respiratory dysfunction. Among those, two have received noninvasive positive pressure ventilation, and one has required mechanical ventilation. Because respiratory failure frequently appeared in PM associated with invasive thymoma, we need to pay attention to the respiratory complication of PM. Magnetic resonance imaging (MRI) is good modality to assess muscle inflammation, even in impaired respiratory muscle, which is difficult to be performed in muscle biopsy.
KEYWORDS
Thymoma Polymyositis Respiratory failure
Received 26 Oct 2013 ／ Accepted 27 Jan 2014
AJRS, 3(3): 427-431, 2014
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